Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10706860 | 0.91 | RAB9A (0.47) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL7604101 | 0.85 | RAB9A (0.57) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10704429 | 0.83 | MAPT (0.41) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10704217 | 0.82 | NPC1 (0.53) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10711195 | 0.81 | SLC6A3 (0.49) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10706951 | 0.80 | TDP1 (0.54) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10712013 | 0.80 | SLC6A3 (0.53) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10707056 | 0.80 | KMT2A (0.45) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10704935 | 0.78 | TRPA1 (0.46) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL13774579 | 0.77 | MEN1 (0.63) | RAB9ANPC1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116729-B1 | BENZOYLUREA COMPOUNDS AND PESTICIDAL COMPOSITIONS COMPRISINGSAME | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-10-12 | — | — | EP | disclosed |
| US-4710516-A | Insecticidal and acaricidal composition comprising a benzoylurea compound | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-12-01 | — | — | US | disclosed |
| US-4665235-A | INSECTICIDES, MITICIDES, ANTITUMOR AGENTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-05-12 | — | — | US | disclosed |