Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
| ▸ | SHBG | P04278 | 3/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543840 | 0.90 | CYP19A1 (0.55) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL15516132 | 0.83 | CYP19A1 (0.42) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL10707829 | 0.81 | SHBG (0.52) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL26425075 | 0.79 | CYP19A1 (0.66) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL19608861 | 0.79 | CYP19A1 (0.66) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL922877 | 0.79 | CYP19A1 (0.66) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL13216466 | 0.79 | CYP19A1 (0.66) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL11977689 | 0.79 | CYP19A1 (0.66) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL29754939 | 0.79 | CYP19A1 (0.66) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL9116613 | 0.77 | CYP19A1 (0.60) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113812-B1 | PROCESS FOR THE PREPARATION OF 17-ALPHA-BROMOETHYNYL AND 17-ALPHA-IODOETHYNYL-17-BETA-HYDROXY STEROIDS, AND 17-ALPHA-BROMOETHYNYL AND 17-ALPHA-IODOETHYNYL-17-BETA-HYDROXY STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-10-26 | — | — | EP | disclosed |