Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29747171 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1CA2APOBEC3G | |
| Carbamic Acid SCHEMBL31333088 | 0.88 | MAPT (0.42) | ALDH1A1TSHRTDP1CA2PDCD1 | |
| SCHEMBL9251988 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL24702055 | 0.82 | CA2 (0.46) | ALDH1A1TSHRTDP1CA2APOBEC3G | |
| SCHEMBL10706992 | 0.82 | CA2 (0.64) | ALDH1A1TSHRTDP1CA2PDCD1 | |
| SCHEMBL10176579 | 0.82 | PDCD1 (0.50) | ALDH1A1TSHRTDP1CA2APOBEC3G | |
| SCHEMBL5435016 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL9838551 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| Hydrogen Peroxide SCHEMBL11570368 | 0.81 | GABRA1 (0.50) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL9626866 | 0.81 | CA2 (0.45) | ALDH1A1TSHRTDP1CA2APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108160094-B | Nitrogen-doped carbon material supported noble metal catalyst, preparation and application thereof | 中国科学院大连化学物理研究所 | 2020-12-15 | — | — | CN | claimed |
| CN-107537565-B | Amphoteric crosslinked polymer supported noble metal catalyst, preparation and alcohol oxidation method | 中国科学院大连化学物理研究所 | 2020-06-19 | — | — | CN | claimed |
| CN-107754856-B | Preparation of macrocyclic compound supported gold catalyst, gold catalyst and application | 中国科学院大连化学物理研究所 | 2020-03-27 | — | — | CN | claimed |
| CN-107349960-B | Nitrogen-containing cross-linked polymer supported nano-gold catalyst, preparation thereof and application thereof in alcohol selective oxidation reaction in aqueous medium | 中国科学院大连化学物理研究所 | 2020-02-07 | — | — | CN | claimed |
| CN-108160094-A | A kind of N doping Carbon Materials support noble metal catalyst and preparation and application | 中国科学院大连化学物理研究所 | 2018-06-15 | — | — | CN | claimed |
| WO-2009029242-A1 | FUNCTIONALIZATION OF POLYGLYCOLIDES BY 'CLICK' CHEMISTRY | MICHIGAN STATE UNIVERSITY (US) | 2009-03-05 | — | — | WO | claimed |
| US-20090054619-A1 | Functionalization of polyglycolides by \"click\" chemistry | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2009-02-26 | — | — | US | claimed |
| CN-118076348-A | N-acylhydrazone compounds capable of inhibiting NAV 1.7 and/or NAV 1.8, methods of making, compositions, uses, methods of treatment and kits using the same | 欧罗法玛实验室股份公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20240166646-A1 | 1H-PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS BCL-2 INHIBITORS FOR THE TREATMENT OF NEOPLASTIC AND AUTOIMMUNE DISEASES | NEWAVE PHARMACEUTICAL INC. | 2024-05-23 | — | — | US | disclosed |
| US-20240018131-A1 | MATRIX METALLOPROTEINASE (MMP) INHIBITORS AND METHODS OF USE THEREOF | FORESEE PHARMACEUTICALS USA, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20240018131-A1 | MATRIX METALLOPROTEINASE (MMP) INHIBITORS AND METHODS OF USE THEREOF | FORESEE PHARMACEUTICALS USA, INC. | 2024-01-18 | — | — | US | disclosed |
| US-11827662-B2 | Cot modulators and methods of use thereof | GILEAD SCIENCES, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11807709-B2 | Method for producing polyisocyanates of (cyclo)aliphatic diisocyanates which are flocculation-stable in solvents | BASF SE | 2023-11-07 | — | — | US | disclosed |
| EP-0244632-B1 | TUBE BUNDLE REACTOR, ITS USE IN EXOTHERMAL ORGANIC REACTIONS AND PROCESS FOR THE PREPARATION OF KETONES AND ALDEHYDES | BASF Aktiengesellschaft (DE) | 1991-02-20 | — | — | EP | disclosed |
| EP-0305093-A1 | Imidazo(1,2-b)pyridazine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-03-01 | — | — | EP | disclosed |
| EP-0244632-A2 | Tube bundle reactor, its use in exothermal organic reactions and process for the preparation of ketones and aldehydes | BASF Aktiengesellschaft (DE) | 1987-11-11 | — | — | EP | disclosed |
| EP-0004881-B1 | PROCESS FOR THE PREPARATION OF AROMATIC AND ARALIPHATIC ALDEHYDES | BASF Aktiengesellschaft (DE) | 1981-10-07 | — | — | EP | disclosed |
| US-4224254-A | OXIDATION OF AROMATIC ALCOHOLS, SILVER CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1980-09-23 | — | — | US | disclosed |
| US-4219570-A | Insect repellents and a method of repelling insects | AJINOMOTO COMPANY, INCORPORATED (JP) | 1980-08-26 | — | — | US | disclosed |
| EP-0004881-A2 | Process for the preparation of aromatic and araliphatic aldehydes | BASF Aktiengesellschaft (DE) | 1979-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166646-A1 | 1H-PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS BCL-2 INHIBITORS FOR THE TREATMENT OF NEOPLASTIC AND AUTOIMMUNE DISEASES | BCL2, BCL3, BCL2L1 | ALDH1A1 1700/4885TSHR 3324/4885TDP1 694/4885 |
| US-20240018131-A1 | MATRIX METALLOPROTEINASE (MMP) INHIBITORS AND METHODS OF USE THEREOF | MMP12, MMP1, MMP11 | ALDH1A1 2785/4885TSHR 4265/4885TDP1 2386/4885 |
| US-11827662-B2 | Cot modulators and methods of use thereof | BRDT, THRB, HCCS | ALDH1A1 2149/4885TSHR 11/4885TDP1 1212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.