Sugi Predict

Sugi Predict / Compounds / SCHEMBL823150

SCHEMBL823150

SCHEMBL823150

Cc1ccc(NC(=O)c2ccc3c4ccc(C(=O)O)c5c(C(=O)Nc6ccc(C)cc6)ccc(c6ccc(C(=O)O)c2c63)c54)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 7/20 0.50
▸ NPC1 O15118 6/20 0.50
▸ SMN1; SMN2 Q16637 3/20 0.50
▸ MAPT P10636 3/20 0.50
▸ LMNA P02545 2/20 0.50
▸ TP53 P04637 2/20 0.50
▸ HTT P42858 2/20 0.50
▸ NFKB1 P19838 1/20 0.50
▸ NFKB2 Q00653 1/20 0.50
▸ RELA Q04206 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ MAOB P27338 1/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ MEN1 O00255 5/20 0.46
▸ KMT2A Q03164 5/20 0.46
▸ CYP3A4 P08684 2/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ GAA P10253 1/20 0.46
▸ CYP2D6 P10635 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10708453 1.00 RAB9A (0.50) RAB9ANPC1SMN1; SMN2MAPTLMNA
SCHEMBL2784273 0.94 RAB9A (0.56) RAB9ANPC1SMN1; SMN2MAPTLMNA
SCHEMBL12180219 0.89 RAB9A (0.42) RAB9ANPC1SMN1; SMN2MAPTLMNA
SCHEMBL12038234 0.89 RAB9A (0.42) RAB9ANPC1SMN1; SMN2MAPTLMNA
SCHEMBL16351281 0.88 RAB9A (0.41) RAB9ANPC1SMN1; SMN2MAPTLMNA
SCHEMBL5884185 0.86 ALDH1A1 (0.49) MAPTMAOBTDP1MEN1KMT2A
SCHEMBL7773657 0.86 LMNA (0.50) MAPTLMNATP53HTTHSD17B10
SCHEMBL7781186 0.86 MEN1 (0.50) RAB9ANPC1SMN1; SMN2TP53HSD17B10
SCHEMBL823148 0.85 ALDH1A1 (0.62) RAB9ANPC1LMNATP53HTT
SCHEMBL1096405 0.85 ALDH1A1 (0.62) RAB9ANPC1LMNATP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 — — US disclosed
US-8431433-B2 Methods of providing semiconductor layers from amic acid salts EASTMAN KODAK COMPANY (US) 2013-04-30 — — US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 — — US disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 — — US disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 — — US disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 — — US disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 — — US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269966-A1 SEMICONDUCTING ARTICLES ALAD, PORCN, DDC RAB9A 2482/4885NPC1 2148/4885SMN1; SMN2 2682/4885
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS DDC, AADAC, MYOC RAB9A 1518/4885NPC1 2077/4885SMN1; SMN2 2911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.