Sugi Predict

Sugi Predict / Compounds / SCHEMBL823148

SCHEMBL823148

SCHEMBL823148

O=C(O)c1ccc2c3ccc(C(=O)Nc4ccccc4)c4c(C(=O)O)ccc(c5ccc(C(=O)Nc6ccccc6)c1c25)c43

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.62
▸ CYP3A4 P08684 1/20 0.57
▸ CYP2C9 P11712 1/20 0.57
▸ ALOX12 P18054 1/20 0.57
▸ MEN1 O00255 6/20 0.51
▸ KMT2A Q03164 6/20 0.51
▸ HPGD P15428 2/20 0.51
▸ HTT P42858 2/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ LMNA P02545 1/20 0.51
▸ TP53 P04637 1/20 0.51
▸ HSD17B10 Q99714 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.50
▸ METAP2 P50579 1/20 0.49
▸ CHRNB2 P17787 1/20 0.49
▸ CHRNB4 P30926 1/20 0.49
▸ CHRNA3 P32297 1/20 0.49
▸ CHRNA4 P43681 1/20 0.49
▸ CYP1A2 P05177 1/20 0.48
▸ DHODH Q02127 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1096405 1.00 ALDH1A1 (0.62) ALDH1A1CYP3A4CYP2C9ALOX12MEN1
SCHEMBL2208572 0.93 ALDH1A1 (0.71) ALDH1A1CYP3A4CYP2C9ALOX12MEN1
SCHEMBL823201 0.93 ALDH1A1 (0.71) ALDH1A1CYP3A4CYP2C9ALOX12MEN1
SCHEMBL12039441 0.93 ALDH1A1 (0.71) ALDH1A1CYP3A4CYP2C9ALOX12MEN1
SCHEMBL10395566 0.93 ALDH1A1 (0.71) ALDH1A1CYP3A4CYP2C9ALOX12MEN1
SCHEMBL12039851 0.89 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP2C9ALOX12MEN1
SCHEMBL12038233 0.89 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP2C9ALOX12MEN1
SCHEMBL16351289 0.87 ALDH1A1 (0.49) ALDH1A1CYP3A4CYP2C9ALOX12MEN1
SCHEMBL7773657 0.87 LMNA (0.50) ALDH1A1CYP3A4CYP2C9ALOX12MEN1
SCHEMBL7781186 0.87 MEN1 (0.50) ALDH1A1CYP3A4CYP2C9ALOX12MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 — — US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 — — US disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 — — US disclosed
WO-2011137137-A1 SEMICONDUCTING ARTICLES EASTMAN KODAK COMPANY (US) 2011-11-03 — — WO disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 — — US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 — — US disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 — — US disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269966-A1 SEMICONDUCTING ARTICLES ALAD, PORCN, DDC ALDH1A1 508/4885CYP3A4 902/4885CYP2C9 230/4885
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS DDC, AADAC, MYOC ALDH1A1 745/4885CYP3A4 283/4885CYP2C9 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.