SCHEMBL1070864

SCHEMBL1070864

CC(C)c1ccc(C(C)(C)c2ccc(O)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.70
ESR2 Q92731 9/20 0.70
CYP3A4 P08684 3/20 0.70
ESRRG P62508 2/20 0.70
AR P10275 2/20 0.70
SLC6A2 P23975 2/20 0.70
SLC6A3 Q01959 2/20 0.70
HPGD P15428 1/20 0.70
TSHR P16473 1/20 0.70
SLC6A4 P31645 1/20 0.70
HTR6 P50406 1/20 0.70
HSD17B10 Q99714 1/20 0.70
ALDH1A1 P00352 1/20 0.59
TYR P14679 2/20 0.50
LMNA P02545 2/20 0.50
PDCD1 Q15116 1/20 0.50
CD274 Q9NZQ7 1/20 0.50
CYP2D6 P10635 2/20 0.47
CYP2C9 P11712 2/20 0.47
HIF1A Q16665 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16191360 0.89 CYP2C9 (0.50) ESR1ESR2CYP3A4ESRRGAR
Isopropylbenzene SCHEMBL10440206 0.88 ESR2 (0.74) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL4905749 0.87 ESR1 (0.70) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL7919913 0.87 ESR1 (0.70) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL7917275 0.87 ESR1 (0.59) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL7809653 0.84 ESR1 (0.73) ESR1ESR2CYP3A4ESRRGAR
Bisphenol A SCHEMBL28857248 0.84 ESR1 (0.80) ESR1ESR2CYP3A4ESRRGAR
Bisphenol A SCHEMBL29419665 0.84 ESR1 (0.80) ESR1ESR2CYP3A4ESRRGAR
Bisphenol A SCHEMBL15062 0.83 ESR1 (1.00) ESR1ESR2CYP3A4ESRRGAR
Bisphenol A SCHEMBL3170263 0.83 ESR1 (1.00) ESR1ESR2CYP3A4ESRRGAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023223925-A1 PHENOLIC HYDROXY GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, AND LAMINATE DIC株式会社 2023-11-23 WO disclosed
US-11339184-B2 Antibacterial compounds, compositions thereof, and methods using same THE ROCKEFELLER UNIVERSITY (US) 2022-05-24 US disclosed
US-20210303091-A1 ELECTRONIC APPARATUS AND METHOD FOR MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-09-30 US disclosed
US-20210069963-A1 METHOD FOR MANUFACTURING A THREE-DIMENSIONAL OBJECT SOLVAY SPECIALITY POLYMERS USA, LLC 2021-03-11 US disclosed
US-20210024562-A1 ANTIBACTERIAL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS USING SAME THE ROCKEFELLER UNIVERSITY 2021-01-28 US disclosed
US-10870725-B2 Heat curable resin composition, and circuit board with electronic component mounted thereon SAN-EI KAGAKU CO., LTD. (JP) 2020-12-22 US disclosed
US-20170335049-A1 HEAT CURABLE RESIN COMPOSITION, AND CIRCUIT BOARD WITH ELECTRONIC COMPONENT MOUNTED THEREON SAN-EI KAGAKU CO., LTD. (JP) 2017-11-23 US disclosed
US-9732183-B2 Method for manufacturing hole-filling printed wiring board, curable resin composition and hole-filling printed wiring board SAN-EI KAGAKU CO., LTD. (JP) 2017-08-15 US disclosed
US-20170066868-A1 METHOD FOR MANUFACTURING HOLE-FILLING PRINTED WIRING BOARD, CURABLE RESIN COMPOSITION AND HOLE-FILLING PRINTED WIRING BOARD SAN-EI KAGAKU CO., LTD. (JP) 2017-03-09 US disclosed
EP-2272889-B1 POLYCARBONATE RESIN HAVING ULTRAVIOLET ABSORBING CAPABILITY, RESIN COMPOSITION AND OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2013-09-04 EP disclosed
EP-2272889-A1 POLYCARBONATE RESIN HAVING ULTRAVIOLET ABSORBING CAPABILITY, RESIN COMPOSITION AND OPTICAL MATERIAL Mitsubishi Gas Chemical Company, Inc. (JP) 2011-01-12 EP disclosed
CN-1080251-C Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use inproduct of said dihalopropene compounds SUMITOMO CHEMICAL CO (JP) 2002-03-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11339184-B2 Antibacterial compounds, compositions thereof, and methods using same CLPP, MPO, SPOUT1 ESR1 4377/4885ESR2 4162/4885CYP3A4 4357/4885
US-20210024562-A1 ANTIBACTERIAL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS USING SAME CLPP, MPO, SPOUT1 ESR1 4377/4885ESR2 4162/4885CYP3A4 4357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.