SCHEMBL491308

SCHEMBL491308

COc1cccc(Oc2ccccc2)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.70
LTA4H P09960 2/20 0.70
CA4 P22748 1/20 0.59
PGR P06401 2/20 0.58
TSHR P16473 1/20 0.57
MAOB P27338 2/20 0.57
MTNR1B P49286 2/20 0.56
MTNR1A P48039 1/20 0.56
ALDH1A1 P00352 4/20 0.54
KDM4E B2RXH2 2/20 0.54
HTT P42858 1/20 0.54
ACHE P22303 1/20 0.54
POLB P06746 1/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
MEN1 O00255 1/20 0.52
MITF O75030 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
GFER P55789 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15834450 0.93 LTA4H (0.82) SMN1; SMN2LTA4HCA4PGRTSHR
SCHEMBL10709191 0.93 SMN1; SMN2 (0.80) SMN1; SMN2LTA4HPGRMTNR1BMTNR1A
SCHEMBL30053231 0.93 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HCA4PGRMAOB
SCHEMBL29929943 0.93 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HCA4PGRMAOB
SCHEMBL1061713 0.93 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HCA4PGRMAOB
SCHEMBL13167638 0.93 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HCA4PGRMAOB
SCHEMBL11049862 0.91 SMN1; SMN2 (0.77) SMN1; SMN2LTA4HPGRMTNR1BMTNR1A
SCHEMBL18415521 0.88 LTA4H (0.73) SMN1; SMN2LTA4HCA4PGRTSHR
SCHEMBL4608736 0.88 SMN1; SMN2 (0.73) SMN1; SMN2LTA4HCA4PGRMTNR1B
SCHEMBL22559 0.87 LTA4H (0.75) SMN1; SMN2LTA4HTSHRMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007102766-A1 PROCESS FOR PRODUCTION OF A BIS-PHTHALONITRILE MONOMER PERSTORP SPECIALTY CHEMICALS AB (SE) 2007-09-13 WO claimed
CN-1047382-C Novel pyrethroid composition FMC CO LTD (US) 1999-12-15 CN claimed
CN-1074677-A Novel pyrethroid composition FMC CO LTD (US) 1993-07-28 CN claimed
US-4299636-A COMPOSITE MODIFIED DOUBLE BASE HERCULES INCORPORATED (US) 1981-11-10 US claimed
US-20240410055-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2024-12-12 US disclosed
CN-118359535-A Synthesis method of N-tert-butoxycarbonyl-3-pyridyl-D/L-alanine 武汉理工大学 2024-07-19 CN disclosed
US-20240239774-A1 SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF CORNELL UNIVERSITY (US) 2024-07-18 US disclosed
EP-4157844-B1 4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-3,6-DIHYDROPYRIDINE-1-(2H)-CARBOXAMIDE DERIVATIVES AS LIMK AND/OR ROCK KINASES INHIBITORS FOR USE IN THE TREATMENT OF CANCER CENTRE NAT RECH SCIENT (FR) 2024-07-10 EP disclosed
CN-118076767-A Method and formulation for producing an optical metal oxide layer 默克专利有限公司 2024-05-24 CN disclosed
US-11839149-B2 Compound and light-emitting device including same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-05 US disclosed
US-20230337672-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-26 US disclosed
US-20230232827-A1 METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-07-27 US disclosed
US-4537897-A PESTICIDES ROUSSEL UCLAF (FR) 1985-08-27 US disclosed
US-4528085-A Ion selective electrode and process of preparing the same FUJI PHOTO FILM COMPANY, LTD. (JP) 1985-07-09 US disclosed
US-4437970-A Device for determining ionic activity FUJI PHOTO FILM CO., LTD. (JP) 1984-03-20 US disclosed
EP-0095946-A1 Device for determining ionic activity FUJI PHOTO FILM CO., LTD. (JP) 1983-12-07 EP disclosed
US-4299636-A COMPOSITE MODIFIED DOUBLE BASE HERCULES INCORPORATED (US) 1981-11-10 US disclosed
US-4278816-A FROM DIPHENYL ETHERS AND HYDROGEN SULFIDE, ABSORPTIVE CATALYST STAUFFER CHEMICAL COMPANY (US) 1981-07-14 US disclosed
US-4214968-A Ion-selective electrode EASTMAN KODAK COMPANY (US) 1980-07-29 US disclosed
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239774-A1 SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF UACA, ADCYAP1R1, ADCY1 SMN1; SMN2 4377/4885LTA4H 2152/4885CA4 2516/4885
US-20230337672-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE CYC1, SQOR, MT-CO1 SMN1; SMN2 4428/4885LTA4H 3564/4885CA4 3615/4885
US-20230232827-A1 METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES CYC1, SQOR, MT-CO3 SMN1; SMN2 4452/4885LTA4H 2872/4885CA4 2638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.