SCHEMBL1071072

SCHEMBL1071072

Oc1ccc(-c2c[nH]c3ccccc23)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.68
IMPDH2 P12268 2/20 0.62
MAPK1 P28482 1/20 0.62
HSD17B10 Q99714 1/20 0.62
AR P10275 1/20 0.60
DYRK1A Q13627 1/20 0.55
TDO2 P48775 6/20 0.53
ASH1L Q9NR48 1/20 0.51
ALOX5 P09917 1/20 0.50
SIRT2 Q8IXJ6 2/20 0.49
SIRT1 Q96EB6 1/20 0.49
PRKD3 O94806 1/20 0.49
CCNB2 O95067 1/20 0.49
CCNE2 O96020 1/20 0.49
ABL1 P00519 1/20 0.49
PRKCG P05129 1/20 0.49
PRKCB P05771 1/20 0.49
CDK1 P06493 1/20 0.49
PIM1 P11309 1/20 0.49
CDK4 P11802 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL28220688 0.92 NR4A2 (0.58) NR4A2IMPDH2MAPK1HSD17B10AR
SCHEMBL28377762 0.90 NR4A2 (0.81) NR4A2IMPDH2MAPK1HSD17B10TDO2
SCHEMBL28416622 0.88 NR4A2 (0.78) NR4A2IMPDH2MAPK1HSD17B10TDO2
3-Phenylindole SCHEMBL84056 0.84 IMPDH2 (0.71) NR4A2IMPDH2MAPK1HSD17B10TDO2
3-Phenylindole SCHEMBL29609072 0.84 IMPDH2 (0.71) NR4A2IMPDH2MAPK1HSD17B10TDO2
SCHEMBL5424191 0.83 TDO2 (0.63) NR4A2IMPDH2MAPK1HSD17B10AR
SCHEMBL13302269 0.81 DYRK1A (0.55) DYRK1APIM1
SCHEMBL31517811 0.81 NR4A2 (0.68) NR4A2IMPDH2MAPK1HSD17B10TDO2
SCHEMBL1879218 0.81 NR4A2 (1.00) NR4A2IMPDH2MAPK1HSD17B10TDO2
SCHEMBL31517691 0.81 NR4A2 (0.68) NR4A2IMPDH2MAPK1HSD17B10TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11833747-B2 Methods of manufacturing articles utilizing foam particles NIKE, INC. (US) 2023-12-05 US claimed
CN-110054579-B Preparation method and application of 4- (1-H indole) phenol derivative 贵州省中国科学院天然产物化学重点实验室 2022-07-29 CN claimed
US-10864676-B2 Methods of manufacturing articles utilizing foam particles NIKE, INC. (US) 2020-12-15 US claimed
CN-106568889-A Pesticide residue detection card 刘沛明 2017-04-19 CN claimed
CN-105705588-A Colored fluids for display devices 太阳化学公司 2016-06-22 CN claimed
CN-101631787-A Tricyclic isoquinoline derivatives for the treatment of obesity BIOVITRUM AB PUBL 2010-01-20 CN claimed
CN-100522128-C Keratin dyeing compounds, keratin dyeing compositions containing them and their use PROCTER & GAMBLE (US) 2009-08-05 CN claimed
US-11981788-B2 Methods of manufacturing articles utilizing foam particles NIKE, INC. (US) 2024-05-14 US disclosed
EP-3861880-B1 ARTICLES COMPRISING FOAM PARTICLES AND METHODS OF MANUFACTURING ARTICLES UTILZING FOAM PARTICLES NIKE INNOVATE CV (US) 2024-02-21 EP disclosed
US-11884005-B2 Methods of manufacturing articles utilizing foam particles NIKE, INC. (US) 2024-01-30 US disclosed
EP-4026452-B1 CUSHIONING ELEMENT UTILIZING FOAM PARTICLES NIKE INNOVATE CV (US) 2024-01-03 EP disclosed
US-11840615-B2 Methods of manufacturing articles utilizing foam particles NIKE, INC. (US) 2023-12-12 US disclosed
US-11833747-B2 Methods of manufacturing articles utilizing foam particles NIKE, INC. (US) 2023-12-05 US disclosed
US-5380850-A Quinoline hydrazine intermediates MERCK FROSST CANADA, INC. (CA) 1995-01-10 US disclosed
WO-1994013293-A2 (QUINOLIN-2-YLMETHOXY)INDOLES AS INHIBITORS OF THE BIOSYNTHESIS OF LEUKOTRIENES MERCK FROSST CANADA INC. (CA) 1994-06-23 WO disclosed
WO-1994000446-A1 FLUORINATED QUINOLINE INDOLES AS INHIBITORS OF THE BIOSYNTHESIS OF LEUKOTRIENES MERCK FROSST CANADA INC. (CA) 1994-01-06 WO disclosed
US-5272145-A (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes MERCK FROSST CANADA, INC. (CA) 1993-12-21 US disclosed
US-5252585-A Fluorinated quinoline indoles as inhibitors of the biosynthesis of leukotrienes MERCK FROSST CANADA, INC. (CA) 1993-10-12 US disclosed
US-5204344-A (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes MERCK FROSST CANADA, INC. (CA) 1993-04-20 US disclosed
EP-0419049-A1 (Quinolin-2-ylmethoxy) indoles as inhibitors of the biosynthesis of leukotrienes MERCK FROSST CANADA INC. (CA) 1991-03-27 EP disclosed