Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | STK10 | O94804 | 4/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 4/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711514 | 0.86 | FEN1 (0.34) | CES1NSD2BCHEDAOLDHA | |
| SCHEMBL10712822 | 0.79 | ALDH1A1 (0.40) | CES1NSD2BCHEDAOSTK10 | |
| SCHEMBL11094095 | 0.75 | FFAR1 (0.35) | BRD4DPP4 | |
| SCHEMBL10711828 | 0.74 | GABRP (0.39) | POLBKMT2ALMNAPGRMAPT | |
| SCHEMBL11853355 | 0.73 | ALDH1A1 (0.36) | NOTUMPOLBKMT2AALDH1A1 | |
| SCHEMBL117727 | 0.73 | CACNB4 (0.40) | CES1NSD2BCHEDAOTGM2 | |
| SCHEMBL10713260 | 0.72 | MAOA (0.33) | CES1GSK3BBRD4CREBBPALDH1A1 | |
| SCHEMBL10921967 | 0.71 | HTT (0.33) | KMT2ALMNAMAPT | |
| SCHEMBL10711185 | 0.70 | PPARG (0.34) | DAOGSK3BNOTUMCACNG8POLB | |
| SCHEMBL10712785 | 0.70 | KDM4E (0.33) | DAOBRD4CREBBPMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0089426-B1 | 2-AMINO-6-BIPHENYLACETIC ACIDS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-06-11 | — | — | EP | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0089426-A1 | 2-Amino-6-biphenylacetic acids | A.H. ROBINS COMPANY, INCORPORATED (US) | 1983-09-28 | — | — | EP | disclosed |
| US-4333951-A | MUSCLE RELAXANTS, ANTIINFLAMMATORY AGENTS | A. H. ROBINS COMPANY, INC. (US) | 1982-06-08 | — | — | US | disclosed |