Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362209 | 0.83 | LMNA (0.59) | LMNAPOLBFFAR1NPSR1SMN1; SMN2 | |
| SCHEMBL29590071 | 0.83 | LMNA (0.59) | LMNAPOLBFFAR1NPSR1SMN1; SMN2 | |
| SCHEMBL490691 | 0.82 | CTSG (0.56) | LMNACA12CA1CA2CA14 | |
| SCHEMBL3954801 | 0.82 | LMNA (0.50) | LMNAPOLBFFAR1CA12CA1 | |
| SCHEMBL3691207 | 0.82 | ALOX5 (0.59) | LMNAPOLBFFAR1CA12CA1 | |
| Hydrochloric Acid SCHEMBL7413528 | 0.81 | LMNA (0.57) | LMNAPOLBFFAR1NPSR1SMN1; SMN2 | |
| SCHEMBL2397158 | 0.81 | LMNA (0.49) | LMNAPOLBFFAR1CA12CA1 | |
| SCHEMBL17743971 | 0.81 | POLB (0.49) | LMNAPOLBFFAR1CA12CA1 | |
| SCHEMBL7885276 | 0.81 | CTSG (0.55) | LMNACA12CA1CA2CA14 | |
| SCHEMBL26046334 | 0.79 | LMNA (0.47) | LMNAPOLBFFAR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155079-B1 | ACETYLENE AMINES AND THEIR USE AS VASODILATORS AND ANTIHYPERTENSIVES | McNeilab, Inc. (US) | 1988-02-17 | — | — | EP | disclosed |