Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | CCKBR | P32239 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715803 | 0.84 | BRD4 (0.35) | CHRM1CYP2A6PTGS2 | |
| SCHEMBL10711514 | 0.81 | FEN1 (0.34) | CHRM1CYP2A6PTGS2 | |
| SCHEMBL10714044 | 0.77 | TRPM2 (0.38) | MEN1KMT2ACHRM1LMNAALB | |
| SCHEMBL10921967 | 0.77 | HTT (0.33) | MEN1KMT2ACHRM1LMNAHPGD | |
| SCHEMBL10713397 | 0.77 | BRD4 (0.33) | MAOACYP2A6PTGS2 | |
| SCHEMBL10713260 | 0.73 | MAOA (0.33) | MAOA | |
| SCHEMBL10714781 | 0.73 | METAP2 (0.35) | MEN1KMT2ACHRM1LMNAALB | |
| SCHEMBL10713932 | 0.72 | GABRA1 (0.39) | PTGS2 | |
| SCHEMBL10711888 | 0.71 | BRD4 (0.40) | HPGDPTGS2 | |
| SCHEMBL10711747 | 0.71 | CREBBP (0.43) | MEN1KMT2ALMNACCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |