Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713932 | 0.84 | GABRA1 (0.39) | TRPM2PTGS2PDE4DLRRK2 | |
| SCHEMBL10712219 | 0.83 | GSK3B (0.38) | MEN1KMT2ALMNAPGRGSK3B | |
| SCHEMBL10711888 | 0.80 | BRD4 (0.40) | PTGS2GSK3B | |
| SCHEMBL10713399 | 0.78 | PGR (0.36) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL10711665 | 0.77 | MEN1 (0.33) | CHRM1MEN1KMT2ALMNAALB | |
| SCHEMBL10711115 | 0.75 | ALDH1A1 (0.36) | PTGS2 | |
| SCHEMBL10714792 | 0.75 | ALDH1A1 (0.36) | TRPM2PGRPTGS2GSK3B | |
| SCHEMBL10711514 | 0.74 | FEN1 (0.34) | CHRM1PTGS2 | |
| SCHEMBL10921967 | 0.73 | HTT (0.33) | CHRM1MEN1KMT2ALMNAPTGS2 | |
| SCHEMBL10712822 | 0.72 | ALDH1A1 (0.40) | KMT2ACACNB4CACNA1ACACNA1GCACNG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |