SCHEMBL10711920

SCHEMBL10711920

CC(C)c1cc(C(c2ccc(Oc3ccc(N)cc3)c(C(C)C)c2)(C(F)(F)F)C(F)(F)F)ccc1Oc1ccc(N)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
LMNA P02545 1/20 0.43
ATM Q13315 1/20 0.43
RAB9A P51151 3/20 0.43
ALDH1A1 P00352 5/20 0.41
NPC1 O15118 2/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
HTR2A P28223 3/20 0.41
SLC6A4 P31645 3/20 0.41
KCNH2 Q12809 3/20 0.41
P2RX3 P56373 1/20 0.37
P2RX2 Q9UBL9 1/20 0.37
AR P10275 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
SCN9A Q15858 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10712264 0.87 MAPT (0.45) MAPTL3MBTL1LMNAATMRAB9A
SCHEMBL8152742 0.84 ALDH1A1 (0.49) MAPTL3MBTL1LMNAATMRAB9A
SCHEMBL2890447 0.82 RAB9A (0.47) MAPTL3MBTL1LMNAATMRAB9A
SCHEMBL27714446 0.81 L3MBTL1 (0.59) MAPTL3MBTL1LMNAATMRAB9A
SCHEMBL31457302 0.80 ALDH1A1 (0.46) MAPTRAB9AALDH1A1NPC1HPGD
SCHEMBL9298705 0.80 ALDH1A1 (0.46) MAPTRAB9AALDH1A1NPC1HPGD
SCHEMBL10713698 0.78 PDE7A (0.50) MAPTL3MBTL1LMNAATMRAB9A
SCHEMBL28639356 0.78 RAB9A (0.42) MAPTL3MBTL1LMNAATMRAB9A
SCHEMBL30172875 0.78 RAB9A (0.42) MAPTL3MBTL1LMNAATMRAB9A
SCHEMBL10714102 0.78 RAB9A (0.42) MAPTL3MBTL1LMNAATMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4758875-A Resin encapsulated semiconductor device HITACHI, LTD. (JP) 1988-07-19 US disclosed