Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADH5 | P11766 | 3/20 | 0.33 |
| ▸ | TACR3 | P29371 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713193 | 0.79 | CRHBP (0.44) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10921967 | 0.74 | HTT (0.33) | MEN1KMT2AMAPTGAA | |
| SCHEMBL10715084 | 0.71 | PTGS2 (0.39) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL116974 | 0.70 | MEN1 (0.39) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10712895 | 0.70 | MEN1 (0.38) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL11427524 | 0.70 | KMT2A (0.47) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10711141 | 0.68 | CYP3A4 (0.38) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10713691 | 0.68 | GSK3B (0.40) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10712554 | 0.68 | KMT2A (0.45) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10712211 | 0.68 | KMT2A (0.45) | MEN1KMT2AKDM4ATDP2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0089426-B1 | 2-AMINO-6-BIPHENYLACETIC ACIDS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-06-11 | — | — | EP | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0089426-A1 | 2-Amino-6-biphenylacetic acids | A.H. ROBINS COMPANY, INCORPORATED (US) | 1983-09-28 | — | — | EP | disclosed |
| US-4333951-A | MUSCLE RELAXANTS, ANTIINFLAMMATORY AGENTS | A. H. ROBINS COMPANY, INC. (US) | 1982-06-08 | — | — | US | disclosed |