Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713691 | 0.89 | GSK3B (0.40) | CRHBPCRHR2MEN1KMT2AKDM4A | |
| SCHEMBL10712895 | 0.85 | MEN1 (0.38) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10714792 | 0.80 | ALDH1A1 (0.36) | PGRALDH1A1PTGS2GSK3B | |
| SCHEMBL10711940 | 0.79 | MEN1 (0.40) | CRHBPCRHR2MEN1KMT2AKDM4A | |
| SCHEMBL10715084 | 0.79 | PTGS2 (0.39) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10711646 | 0.78 | MEN1 (0.38) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10711924 | 0.76 | PGR (0.38) | PGRTDP1ALDH1A1MAPTRECQL | |
| SCHEMBL10712554 | 0.73 | KMT2A (0.45) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10711782 | 0.73 | PGR (0.46) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10711443 | 0.72 | PGR (0.49) | MEN1KMT2APGRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |