Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713193 | 0.85 | CRHBP (0.44) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10711518 | 0.85 | MAPK1 (0.34) | KMT2AALDH1A1MAPK1CYP1A2MAPT | |
| SCHEMBL10713691 | 0.79 | GSK3B (0.40) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10712554 | 0.74 | KMT2A (0.45) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10711924 | 0.74 | PGR (0.38) | ALDH1A1CYP3A4TDP1LMNAMAPT | |
| SCHEMBL10711782 | 0.74 | PGR (0.46) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10712953 | 0.73 | IDO1 (0.35) | MEN1KMT2ARAB9AALDH1A1MAPK1 | |
| SCHEMBL10715084 | 0.72 | PTGS2 (0.39) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10711063 | 0.71 | MEN1 (0.42) | MEN1KMT2AKDM4ATDP2KDM4C | |
| SCHEMBL10711646 | 0.71 | MEN1 (0.38) | MEN1KMT2AKDM4ATDP2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |