Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487443 | 0.93 | KMT2A (0.55) | L3MBTL1LMNAKMT2AALDH2EPHX2 | |
| SCHEMBL13744595 | 0.82 | KMT2A (0.53) | L3MBTL1LMNAKMT2AALDH2EPHX2 | |
| SCHEMBL9621303 | 0.82 | LMNA (0.66) | L3MBTL1LMNAKMT2AALDH2EPHX2 | |
| SCHEMBL2481397 | 0.82 | LMNA (0.66) | L3MBTL1LMNAKMT2AALDH2EPHX2 | |
| SCHEMBL5789381 | 0.82 | LMNA (0.66) | L3MBTL1LMNAKMT2AALDH2EPHX2 | |
| SCHEMBL10487407 | 0.80 | KMT2A (0.51) | L3MBTL1LMNAKMT2AALDH2EPHX2 | |
| SCHEMBL10714951 | 0.80 | KMT2A (0.51) | L3MBTL1LMNAKMT2AALDH2EPHX2 | |
| SCHEMBL22542311 | 0.78 | LMNA (0.57) | L3MBTL1LMNAKMT2AALDH2EPHX2 | |
| P-Cresol SCHEMBL6986663 | 0.78 | LMNA (0.61) | L3MBTL1LMNAKMT2AALDH2EPHX2 | |
| SCHEMBL1454525 | 0.78 | L3MBTL1 (0.57) | L3MBTL1LMNAKMT2AALDH2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1987004344-A1 | HYDROXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1987-07-30 | — | — | WO | disclosed |