Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16134247 | 0.86 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2TSHRMAPT | |
| Butane SCHEMBL7847348 | 0.83 | TDP1 (0.56) | RAB9ANPC1SMN1; SMN2TSHRMAPT | |
| Propionic Acid SCHEMBL17748849 | 0.83 | THRB (0.56) | RAB9ANPC1SMN1; SMN2TSHRMAPT | |
| SCHEMBL3640377 | 0.83 | THRB (0.56) | RAB9ANPC1SMN1; SMN2TSHRMAPT | |
| SCHEMBL7380031 | 0.83 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2TSHRMAPT | |
| SCHEMBL868517 | 0.82 | THRB (0.59) | RAB9ANPC1SMN1; SMN2TSHRMAPT | |
| SCHEMBL25282287 | 0.81 | THRB (0.57) | RAB9ANPC1SMN1; SMN2TSHRMAPT | |
| Butyric Acid SCHEMBL538384 | 0.81 | L3MBTL1 (0.53) | RAB9ANPC1SMN1; SMN2TSHRMAPT | |
| Butane SCHEMBL7376678 | 0.81 | LMNA (0.57) | RAB9ANPC1SMN1; SMN2MAPTRECQL | |
| SCHEMBL21834924 | 0.80 | LTA4H (0.56) | RAB9ANPC1SMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173041-B1 | 2-SUBSTITUTED-1,3-PROPYLIDENEDIPHOSPHONATE DERIVATIVES, THE PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1988-11-30 | — | — | EP | disclosed |
| US-4696920-A | CARDIOVASCULAR DISORDERS | SYMPHAR S.A. (CH) | 1987-09-29 | — | — | US | disclosed |
| EP-0173041-A1 | 2-Substituted-1,3-propylidenediphosphonate derivatives, the process for their preparation and pharmaceutical compositions containing them | SYMPHAR S.A. (CH) | 1986-03-05 | — | — | EP | disclosed |