Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718981 | 0.84 | ALDH1A1 (0.43) | MAPTSMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL10726650 | 0.78 | MEN1 (0.53) | NAMPTKDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL10718843 | 0.76 | ALDH1A1 (0.49) | KDM4EMAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL164451 | 0.70 | NAMPT (1.00) | NAMPT | |
| SCHEMBL10725846 | 0.69 | ALDH1A1 (0.54) | NAMPTMAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL24069161 | 0.69 | CYP1A2 (0.75) | KDM4ETDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL10836333 | 0.69 | TBXAS1 (0.71) | KDM4E | |
| SCHEMBL348709 | 0.68 | CYP1A2 (0.68) | KDM4EMAPTALDH1A1LMNAHTT | |
| SCHEMBL11629091 | 0.68 | KMT2A (0.80) | NAMPTKDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL12335097 | 0.68 | NAMPT (0.84) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |