Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726650 | 0.83 | MEN1 (0.53) | ALDH1A1MAPTPTGS1PTGS2KMT2A | |
| SCHEMBL10717698 | 0.81 | MAPT (0.72) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL10716650 | 0.72 | MAPT (0.78) | ALDH1A1MAPTKMT2AMEN1CA1 | |
| SCHEMBL10726837 | 0.71 | PKM (0.50) | ALDH1A1MAPTKMT2AMEN1PKM | |
| SCHEMBL10726335 | 0.70 | CYP1A2 (0.44) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL10716611 | 0.69 | NAMPT (0.54) | ALDH1A1MAPTKMT2AMEN1NAMPT | |
| SCHEMBL10716561 | 0.69 | CASP3 (0.52) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL11783528 | 0.68 | MAPT (0.43) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL10718843 | 0.67 | ALDH1A1 (0.49) | ALDH1A1MAPTPTGS1PTGS2KMT2A | |
| SCHEMBL10716463 | 0.67 | MAPT (0.64) | ALDH1A1MAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |