Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10725846 | 0.83 | ALDH1A1 (0.54) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10716611 | 0.78 | NAMPT (0.54) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL10717698 | 0.77 | MAPT (0.72) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL9568492 | 0.74 | KMT2A (0.72) | MEN1KMT2ALMNASMN1; SMN2NAMPT | |
| SCHEMBL7634383 | 0.71 | MEN1 (0.51) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL7634377 | 0.71 | MEN1 (0.51) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL10716650 | 0.71 | MAPT (0.78) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL10726837 | 0.69 | PKM (0.50) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL10730945 | 0.69 | PKM (0.58) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL1464914 | 0.68 | CYP1A2 (0.61) | MEN1KMT2AMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |