Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978777 | 0.79 | NNMT (0.64) | NNMTSMN1; SMN2EPHX2KDM4EL3MBTL1 | |
| SCHEMBL10716507 | 0.78 | GRM5 (0.54) | MAPTHCAR3GRM5 | |
| Hydrochloric Acid SCHEMBL8074661 | 0.78 | NNMT (0.62) | NNMTSMN1; SMN2EPHX2KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8379439 | 0.78 | NNMT (0.62) | NNMTSMN1; SMN2EPHX2KDM4EL3MBTL1 | |
| SCHEMBL10869100 | 0.74 | ALDH1A1 (0.51) | SMN1; SMN2KDM4EL3MBTL1NPC1MAPT | |
| SCHEMBL383413 | 0.73 | NNMT (0.70) | NNMTSMN1; SMN2EPHX2KDM4EL3MBTL1 | |
| SCHEMBL18715409 | 0.73 | NNMT (0.70) | NNMTSMN1; SMN2EPHX2KDM4EL3MBTL1 | |
| SCHEMBL10716578 | 0.72 | PKM (0.49) | NNMTMAPTHCAR3GRM5 | |
| SCHEMBL4320704 | 0.72 | NNMT (1.00) | NNMTSMN1; SMN2EPHX2KDM4EL3MBTL1 | |
| Hydrazine SCHEMBL628678 | 0.72 | NNMT (0.68) | NNMTSMN1; SMN2EPHX2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |