SCHEMBL383413

SCHEMBL383413

NNc1ccc(C(N)=O)cn1

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NNMT P40261 4/20 0.70
SMN1; SMN2 Q16637 1/20 0.57
EPHX2 P34913 1/20 0.51
GRM5 P41594 1/20 0.47
KDM4E B2RXH2 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HCAR3 P49019 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL628678 0.98 NNMT (0.68) NNMTSMN1; SMN2EPHX2GRM5KDM4E
Acetone SCHEMBL17558521 0.94 NNMT (0.69) NNMTSMN1; SMN2EPHX2GRM5KDM4E
SCHEMBL20518762 0.88 NNMT (0.57) NNMTSMN1; SMN2EPHX2GRM5KDM4E
Succinimide SCHEMBL28645192 0.87 NNMT (0.55) NNMTSMN1; SMN2EPHX2GRM5
SCHEMBL8722229 0.84 NNMT (0.50) NNMTKDM4EHCAR3
SCHEMBL29505896 0.84 HCAR3 (0.67) HCAR3
SCHEMBL18715409 0.84 NNMT (0.70) NNMTSMN1; SMN2EPHX2GRM5KDM4E
SCHEMBL158601 0.84 HCAR3 (0.67) HCAR3
Succinimide SCHEMBL28224691 0.83 NNMT (0.55) NNMTSMN1; SMN2EPHX2HCAR3
SCHEMBL8815728 0.82 NNMT (0.49) NNMTHCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 990 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098617-A1 RADIOPHARMACEUTICAL TARGETING CARBONIC ANHYDRASE IX PROTEIN 无锡诺宇医药科技有限公司 2026-05-15 WO claimed
US-20260131034-A1 RADIOPHARMACEUTICALS TARGETING CARBONIC ANHYDRASE IX PROTEINS NORROY BIOSCIENCE CO LTD (CN) 2026-05-14 US claimed
CN-122005879-A Modified GRPR antagonist peptides for cancer imaging and treatment 慕尼黑工业大学 2026-05-12 CN claimed
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CELLIS AG (CH) 2026-04-02 US claimed
US-20260021211-A1 Dual mode radiotracer and -therapeutics UNIV MUENCHEN TECH (DE) 2026-01-22 US claimed
EP-4651910-A1 DUAL LABELLED COMPOUNDS TARGETING THE PROSTATE SPECIFIC MEMBRANE ANTIGEN Centre Hospitalier Universitaire Vaudois (CHUV) (CH) 2025-11-26 EP claimed
EP-4637829-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF OVARIAN CANCER Cellis Sp. z o.o. ([Ltd.] (PL) 2025-10-29 EP claimed
WO-2025202114-A1 RADIOSENSITISING PEPTIDE COMPLEX GCS INSTITUT DE CANCEROLOGIE STRASBOURG EUROPE (FR) 2025-10-02 WO claimed
US-20250295821-A1 TARGETED RADIOPHARMACEUTICAL FOR TUMOR AND ITS USE IN THE IMAGING-GUIDED COMBINATION THERAPY OF TARGETED RADIOTHERAPY AND IMMUNOTHERAPY BeijingGiluntidePharmaceuticalCo.,Ltd. (CN) 2025-09-25 US claimed
US-12419976-B2 Hybrid tracers for targeted cancer imaging and treatment ACADEMISCH ZIEKENHUIS LEIDEN (H.O.D.N. LUMC) GMBH (NL) 2025-09-23 US claimed
EP-2334814-A1 METHODS AND COMPOSITIONS FOR DIRECT DETECTION OF DNA DAMAGE Solulink Biosciences, Inc. (US) 2011-06-22 EP claimed
CN-101851313-A Technetium-99m-marked poly N-vinyl benzyl-D-lactose amide composition and preparation method UNIV BEIJING NORMAL 2010-10-06 CN claimed
US-20100216132-A1 METHODS AND COMPOSITIONS FOR DIRECT DETECTION OF DNA DAMAGE UNIVERSITY OF CHICAGO 2010-08-26 US claimed
EP-1934251-B1 INTERLEUKIN-8 LABELLED VIA ONE OR MORE SITE SPECIFICALLY CONJUGATED HYDRAZINONICOTINAMIDE (HYNIC) MOIETIES AND ITS USE IN DIAGNOSIS OF INFECTION AND INFLAMMATION STICHTING KATHOLIEKE UNIV (NL) 2010-06-16 EP claimed
WO-2010028388-A1 METHODS AND COMPOSITIONS FOR DIRECT DETECTION OF DNA DAMAGE SOLULINK BIOSCIENCES, INC. (US) 2010-03-11 WO claimed
US-20080274050-A1 Labelled Adrenomedullin Derivatives and Their Use for Imaging and Therapy INSTITUT DE CARDIOLOGIE DE MONTRÉAL (CA) 2008-11-06 US claimed
EP-1978997-A1 TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS Apollo Life Sciences Limited (AU) 2008-10-15 EP claimed
US-20070243132-A1 Transdermal delivery of pharmaceutical agents APOLLO LIFE SCIENCES LIMITED (AU) 2007-10-18 US claimed
WO-2007070983-A1 TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS APOLLO LIFE SCIENCES LIMITED (AU) 2007-06-28 WO claimed
US-4141977-A Treatment of psoriasis with 6-substituted nicotinamides, 2-substituted pyrazinamides and closely related compounds YU RUEY J 1979-02-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260131034-A1 RADIOPHARMACEUTICALS TARGETING CARBONIC ANHYDRASE IX PROTEINS CA9, CA11, CA12 NNMT 3339/4885SMN1; SMN2 2283/4885EPHX2 2028/4885
US-20250295821-A1 TARGETED RADIOPHARMACEUTICAL FOR TUMOR AND ITS USE IN THE IMAGING-GUIDED COMBINATION THERAPY OF TARGETED RADIOTHERAPY AND IMMUNOTHERAPY CD274, ITGB1, ITGA1 NNMT 4793/4885SMN1; SMN2 4084/4885EPHX2 4650/4885
US-12419976-B2 Hybrid tracers for targeted cancer imaging and treatment HNRNPF, ANXA3, SLC67A1 NNMT 4701/4885SMN1; SMN2 3950/4885EPHX2 900/4885
US-20260021211-A1 Dual mode radiotracer and -therapeutics FOLH1, SLC19A1, KLK3 NNMT 3874/4885SMN1; SMN2 772/4885EPHX2 4326/4885
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CD47, TFRC, L1CAM NNMT 4344/4885SMN1; SMN2 460/4885EPHX2 1669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.