Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716730 | 0.78 | NNMT (0.55) | GRM5HCAR3MAPT | |
| SCHEMBL10729011 | 0.76 | L3MBTL1 (0.50) | GRM5HCAR3ALDH1A1HPGDMAPT | |
| SCHEMBL27539513 | 0.76 | HCAR3 (0.66) | GRM5HCAR3ALDH1A1HPGDMAPT | |
| SCHEMBL2961669 | 0.74 | GRM5 (0.49) | GRM5ALDH1A1HPGDMAPTMLYCD | |
| Hydrochloric Acid SCHEMBL991448 | 0.70 | GRM5 (0.77) | GRM5HCAR3ALDH1A1HPGDMAPT | |
| SCHEMBL5429605 | 0.70 | GRM5 (0.54) | GRM5ALDH1A1HPGDMAPTMLYCD | |
| SCHEMBL998975 | 0.70 | GRM5 (0.54) | GRM5ALDH1A1HPGDMAPTMLYCD | |
| Hydrochloric Acid SCHEMBL991511 | 0.69 | GRM5 (0.97) | GRM5HCAR3ALDH1A1HPGDMAPT | |
| SCHEMBL10869100 | 0.68 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTLMNAKMT2A | |
| SCHEMBL991484 | 0.68 | GRM5 (0.59) | GRM5ALDH1A1HPGDMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |