Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716866 | 0.91 | CYP1A2 (0.53) | CYP1A2ADRA2AADRA1AMAPTBLM | |
| SCHEMBL13396799 | 0.91 | CYP1A2 (0.57) | CYP1A2ADRA2AADRA1AMAPTBLM | |
| Bromide SCHEMBL10716902 | 0.89 | CYP1A2 (0.52) | CYP1A2ADRA2AADRA1AMAPTBLM | |
| Hydrochloric Acid SCHEMBL31375742 | 0.89 | MAPT (0.57) | CYP1A2ADRA2AADRA1AMAPTBLM | |
| Bromide SCHEMBL4620693 | 0.86 | BBOX1 (0.46) | CYP1A2ADRA2AADRA1AMAPTTSHR | |
| Bromide SCHEMBL11327541 | 0.84 | DGKA (0.56) | CYP1A2MAPTTSHRALDH1A1DGKA | |
| Bromide SCHEMBL11571925 | 0.84 | DGKA (0.56) | CYP1A2MAPTTSHRALDH1A1DGKA | |
| Bromide SCHEMBL11326341 | 0.84 | DGKA (0.56) | CYP1A2MAPTTSHRALDH1A1DGKA | |
| Bromide SCHEMBL4618327 | 0.84 | BBOX1 (0.47) | CYP1A2ADRA2AADRA1AMAPTBLM | |
| SCHEMBL15625159 | 0.83 | BBOX1 (0.57) | CYP1A2ADRA2AADRA1AMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972630-A | DETERMINING THE PRESENCE OF AN ANALYTE IN SAMPLE; COMPLEXING TWO COMPLEMENTARY SPECIFIC BINDING MEMBERS; THE MEMBERS ARE LIGAND AND RECEPTOR IN SOLUTION, ANALYZING ENZYME ACTIVITY, EVALUATING ACTIVITY BY AMOUNT OF ANALYTE IN SAMPLE | DADE BEHRING MARBURG GMBH (DE) | 1999-10-26 | — | — | US | disclosed |
| US-5919641-A | INCUBATING SAMPLE WITH ENZYME BOUND TO FIRST SPECIFIC BINDING PAIR MEMBER AND ENZYME INHIBITOR BOUND TO SECOND SPECIFIC BINDING PAIR MEMBER, DETECTING ENZYME ACTIVITY WHEN ANALYTE BINDS TO ONE PAIR MEMBER INTERFERING WITH ORIGINAL BINDING | DADE BEHRING MARBURG GMBH (DE) | 1999-07-06 | — | — | US | disclosed |
| EP-0532187-B1 | Homogeneous immunoassays using enzyme inhibitors | BEHRINGWERKE AG (DE) | 1996-10-30 | — | — | EP | disclosed |
| EP-0532187-A1 | Homogeneous immunoassays using enzyme inhibitors | BEHRINGWERKE Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |