Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LIG1 | P18858 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539703 | 0.87 | PKM (0.49) | HPGDALDH1A1SRD5A2SIRT1MAPT | |
| SCHEMBL5399446 | 0.79 | NR1H2 (0.56) | HPGDALDH1A1LIG1SIRT1MAPT | |
| SCHEMBL27674603 | 0.79 | HPGD (0.45) | HPGDALDH1A1SRD5A2SIRT1MAPT | |
| SCHEMBL27809567 | 0.79 | ALDH1A1 (0.47) | HPGDALDH1A1SRD5A2SIRT1MAPT | |
| SCHEMBL487237 | 0.79 | SIRT1 (0.50) | HPGDALDH1A1SIRT1MAPTLMNA | |
| SCHEMBL9625444 | 0.78 | SIRT1 (0.56) | HPGDALDH1A1SRD5A2SIRT1MAPT | |
| SCHEMBL6787662 | 0.77 | ALDH1A1 (0.67) | HPGDALDH1A1SRD5A2MAPTLMNA | |
| SCHEMBL17828242 | 0.77 | ALDH1A1 (0.67) | HPGDALDH1A1SRD5A2MAPTLMNA | |
| SCHEMBL17828245 | 0.77 | ALDH1A1 (0.67) | HPGDALDH1A1SRD5A2MAPTLMNA | |
| SCHEMBL3282737 | 0.77 | HPGD (0.69) | HPGDALDH1A1SRD5A2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62184022-A | — | — | None | — | — | JP | disclosed |
| JP-S62184022-A | PRODUCTION OF AROMATIC POLYKETONE | ASAHI CHEM IND CO LTD | 1987-08-12 | — | — | JP | disclosed |