Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719463 | 0.87 | HPGD (0.44) | PKMALDH1A1HPGDSRD5A2SIRT1 | |
| SCHEMBL487237 | 0.82 | SIRT1 (0.50) | ALDH1A1HPGDTSHRSIRT1TDP1 | |
| SCHEMBL2024004 | 0.81 | ALDH1A1 (0.59) | PKMALDH1A1HPGDTSHRDAO | |
| SCHEMBL24718397 | 0.80 | RXRA (0.52) | PKMALDH1A1HPGDTSHRDAO | |
| SCHEMBL365542 | 0.80 | PKM (0.49) | PKMALDH1A1HPGDTSHRDAO | |
| SCHEMBL689927 | 0.80 | HPGD (0.69) | PKMALDH1A1HPGDTSHRDAO | |
| SCHEMBL5399446 | 0.78 | NR1H2 (0.56) | ALDH1A1HPGDTSHRSIRT1TDP1 | |
| Bicarbonate SCHEMBL11202875 | 0.78 | KDM4E (0.46) | PKMALDH1A1HPGDTSHRNAPRT | |
| SCHEMBL4414886 | 0.77 | HPGD (0.55) | ALDH1A1HPGDTSHRCA12CA1 | |
| SCHEMBL7191097 | 0.77 | PKM (0.46) | PKMALDH1A1HPGDTSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020094993-A1 | Compositions for repelling crawling insects | S.C. JOHNSON & SON, INC. | 2002-07-18 | — | — | US | disclosed |
| EP-0137395-B1 | 4-(HYDROXYPHENYLTHIO)-BENZOATES | CIBA-GEIGY AG (CH) | 1987-11-04 | — | — | EP | disclosed |
| EP-0137395-A2 | 4-(Hydroxyphenylthio)-benzoates | CIBA-GEIGY AG (CH) | 1985-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094993-A1 | Compositions for repelling crawling insects | ACHE, DDT, GAP43 | PKM 3300/4885ALDH1A1 1488/4885HPGD 3530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.