Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 9/20 | 0.57 |
| ▸ | HEXB | P07686 | 9/20 | 0.57 |
| ▸ | OGA | O60502 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.54 |
| ▸ | KLK7 | P49862 | 1/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.51 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395426 | 0.92 | SIRT1 (0.65) | HEXAHEXBOGASIRT1KLK7 | |
| SCHEMBL14557208 | 0.83 | KLK7 (0.57) | HEXAHEXBSIRT1KLK7FTO | |
| SCHEMBL11440392 | 0.82 | FTO (0.71) | HEXAHEXBKLK7FTOTERT | |
| SCHEMBL3851575 | 0.81 | KMT2A (0.67) | KLK7FTOKDM4EALDH1A1GAA | |
| SCHEMBL5123962 | 0.81 | KDM4E (0.64) | KLK7FTOKDM4EALDH1A1 | |
| SCHEMBL11441489 | 0.80 | KMT2A (0.64) | KLK7FTOKDM4EALDH1A1GAA | |
| SCHEMBL8668083 | 0.80 | KLK7 (0.53) | HEXAHEXBOGAKLK7FTO | |
| SCHEMBL8671343 | 0.78 | KLK7 (0.51) | HEXAHEXBKLK7FTOKDM4E | |
| SCHEMBL8668087 | 0.78 | KLK7 (0.51) | HEXAHEXBOGAKLK7FTO | |
| SCHEMBL8398382 | 0.76 | KLK7 (0.54) | HEXAHEXBOGAKLK7FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243841-A1 | Benzo[d,e]isoquinoline-1,3 diones, their preparation and use | KNOLL AG (DE) | 1987-11-04 | — | — | EP | disclosed |