Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10723277 | 1.00 | LMNA (0.47) | LMNASIGMAR1HIF1ACYP2D6MAPK1 | |
| SCHEMBL6596304 | 0.88 | LMNA (0.58) | LMNASIGMAR1HIF1ACYP2D6MAPK1 | |
| SCHEMBL1151817 | 0.88 | LMNA (0.58) | LMNASIGMAR1HIF1ACYP2D6MAPK1 | |
| SCHEMBL1151821 | 0.88 | LMNA (0.58) | LMNASIGMAR1HIF1ACYP2D6MAPK1 | |
| SCHEMBL9530000 | 0.88 | LMNA (0.58) | LMNASIGMAR1HIF1ACYP2D6MAPK1 | |
| Hydrochloric Acid SCHEMBL3842615 | 0.87 | LMNA (0.56) | LMNASIGMAR1HIF1ACYP2D6MAPK1 | |
| Fluoride SCHEMBL27904711 | 0.87 | LMNA (0.56) | LMNASIGMAR1HIF1ACYP2D6MAPK1 | |
| Hydrochloric Acid SCHEMBL3842618 | 0.87 | LMNA (0.56) | LMNASIGMAR1HIF1ACYP2D6MAPK1 | |
| SCHEMBL9123051 | 0.83 | LTA4H (0.59) | LMNASIGMAR1HIF1ACYP2D6MAPK1 | |
| SCHEMBL11661323 | 0.83 | LTA4H (0.59) | LMNASIGMAR1HIF1ACYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232205-A2 | Diene derivatives and vasodilators containing the same | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1987-08-12 | — | — | EP | disclosed |