Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209149 | 0.78 | ALDH1A1 (0.59) | XDHALDH1A1HPGDMAPTLMNA | |
| SCHEMBL10723745 | 0.78 | XDH (0.47) | XDHALDH1A1HPGDMAPTLMNA | |
| SCHEMBL28350684 | 0.76 | HPGD (0.41) | ALDH1A1HPGDMAPTLMNAL3MBTL1 | |
| SCHEMBL5068576 | 0.76 | L3MBTL1 (0.56) | ALDH1A1HPGDMAPTLMNATSHR | |
| SCHEMBL8554234 | 0.74 | MAPT (0.56) | XDHALDH1A1HPGDMAPTLMNA | |
| SCHEMBL8554228 | 0.74 | XDH (0.46) | XDHALDH1A1HPGDMAPTLMNA | |
| SCHEMBL9509578 | 0.70 | L3MBTL1 (0.53) | ALDH1A1HPGDMAPTLMNATP53 | |
| SCHEMBL5872387 | 0.68 | L3MBTL1 (0.53) | ALDH1A1HPGDHTTCYP2D6FEN1 | |
| SCHEMBL31325519 | 0.68 | L3MBTL1 (0.53) | XDHALDH1A1MAPTLMNAHTT | |
| SCHEMBL5736942 | 0.67 | RET (0.37) | ALDH1A1HPGDMAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62192366-A | — | — | None | — | — | JP | disclosed |
| JP-S62192366-A | SUBSTITUTED AMINOBENZYLSULFONYLBENZIMIDAZOLE COMPOUND | NIPPON CHEMIPHAR CO LTD | 1987-08-22 | — | — | JP | disclosed |