Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732434 | 0.95 | NPC1 (0.47) | RAB9ANPC1TSHRMEN1KMT2A | |
| SCHEMBL10727222 | 0.86 | MAPT (0.50) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10726223 | 0.86 | NPC1 (0.49) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10726837 | 0.84 | PKM (0.50) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10717754 | 0.83 | ALDH1A1 (0.52) | RAB9ANPC1TSHRMEN1KMT2A | |
| SCHEMBL10731823 | 0.82 | MAPT (0.59) | RAB9ANPC1TSHRMEN1KMT2A | |
| SCHEMBL10730546 | 0.81 | PKM (0.44) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10730945 | 0.80 | PKM (0.58) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10716540 | 0.77 | ALDH1A1 (0.51) | RAB9ANPC1TSHRMEN1KMT2A | |
| SCHEMBL10716660 | 0.77 | ALDH1A1 (0.49) | RAB9ANPC1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |