Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730945 | 0.95 | PKM (0.58) | PKMALDH1A1ATML3MBTL1NPC1 | |
| SCHEMBL10727222 | 0.87 | MAPT (0.50) | PKMALDH1A1ATML3MBTL1NPC1 | |
| SCHEMBL10717754 | 0.86 | ALDH1A1 (0.52) | PKMALDH1A1ATML3MBTL1NPC1 | |
| SCHEMBL10726208 | 0.85 | PKM (0.52) | PKMALDH1A1ATML3MBTL1NPC1 | |
| SCHEMBL10732117 | 0.85 | PKM (0.52) | PKMALDH1A1ATML3MBTL1NPC1 | |
| SCHEMBL10725744 | 0.84 | RAB9A (0.51) | ALDH1A1ATML3MBTL1NPC1RAB9A | |
| SCHEMBL10731823 | 0.83 | MAPT (0.59) | PKMALDH1A1ATML3MBTL1NPC1 | |
| SCHEMBL10732434 | 0.80 | NPC1 (0.47) | PKMALDH1A1ATML3MBTL1NPC1 | |
| SCHEMBL10732657 | 0.80 | PKM (0.47) | PKMALDH1A1ATML3MBTL1NPC1 | |
| SCHEMBL10716660 | 0.78 | ALDH1A1 (0.49) | PKMALDH1A1ATML3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |