Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10729295 | 0.83 | ALDH1A1 (0.45) | PKMRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL10717754 | 0.80 | ALDH1A1 (0.52) | PKMRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL10726196 | 0.80 | PKM (0.52) | PKMMAPTALDH1A1SMN1; SMN2PTGS1 | |
| SCHEMBL10726719 | 0.80 | PKM (0.52) | PKMRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL10730568 | 0.79 | PKM (0.51) | PKMMAPTALDH1A1KDM4E | |
| SCHEMBL10729039 | 0.78 | PKM (0.56) | PKMMAPTCCR6ALDH1A1SCN9A | |
| SCHEMBL10731824 | 0.77 | PKM (0.49) | PKMRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL10716578 | 0.77 | PKM (0.49) | PKMMAPT | |
| SCHEMBL10731727 | 0.77 | PKM (0.49) | PKMRAB9AMAPTALDH1A1LMNA | |
| SCHEMBL10725561 | 0.77 | PKM (0.49) | PKMMAPTALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |