Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717754 | 0.80 | ALDH1A1 (0.52) | PKMMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL10726719 | 0.80 | PKM (0.52) | PKMMAPTALDH1A1LMNAPOLB | |
| SCHEMBL10726196 | 0.80 | PKM (0.52) | PKMMAPTALDH1A1LMNAPOLB | |
| SCHEMBL10731824 | 0.80 | PKM (0.49) | PKMMAPTHTTKDM4EALDH1A1 | |
| SCHEMBL10730568 | 0.79 | PKM (0.51) | PKMMAPTKDM4EALDH1A1GAA | |
| SCHEMBL10726331 | 0.78 | LMNA (0.59) | PKMMAPTHTTKDM4EALDH1A1 | |
| SCHEMBL10729039 | 0.78 | PKM (0.56) | PKMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10726379 | 0.78 | PKM (0.47) | PKMMAPTKDM4EMAPK1ALDH1A1 | |
| SCHEMBL10728346 | 0.78 | BAZ2B (0.48) | PKMMAPTHTTKDM4EMAPK1 | |
| SCHEMBL10731246 | 0.77 | PKM (0.45) | PKMMAPTHTTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |