Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717754 | 0.87 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1ATMPKMLMNA | |
| SCHEMBL10726208 | 0.84 | PKM (0.52) | ALDH1A1L3MBTL1ATMPKMLMNA | |
| SCHEMBL10732444 | 0.84 | MAPT (0.49) | ALDH1A1L3MBTL1ATMPKMLMNA | |
| SCHEMBL10725939 | 0.83 | PKM (0.49) | ALDH1A1PKMLMNAKDM4EMAPT | |
| SCHEMBL10726223 | 0.81 | NPC1 (0.49) | ALDH1A1PKMLMNAMAPTMEN1 | |
| SCHEMBL10731309 | 0.80 | KMT2A (0.46) | ALDH1A1L3MBTL1PKMLMNACA1 | |
| SCHEMBL10730945 | 0.80 | PKM (0.58) | ALDH1A1L3MBTL1ATMPKMLMNA | |
| SCHEMBL10731823 | 0.80 | MAPT (0.59) | ALDH1A1L3MBTL1ATMPKMLMNA | |
| SCHEMBL10716660 | 0.78 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1ATMPKMLMNA | |
| SCHEMBL10732117 | 0.78 | PKM (0.52) | ALDH1A1L3MBTL1ATMPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |