Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730568 | 0.84 | PKM (0.51) | PKMMAPTALDH1A1POLBABCC9 | |
| SCHEMBL10726331 | 0.81 | LMNA (0.59) | PKMMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL10726719 | 0.80 | PKM (0.52) | PKMMAPTALDH1A1NPC1POLB | |
| SCHEMBL10726196 | 0.80 | PKM (0.52) | PKMMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10717754 | 0.80 | ALDH1A1 (0.52) | PKMMAPTALDH1A1NPC1POLB | |
| SCHEMBL10728346 | 0.80 | BAZ2B (0.48) | PKMMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10725561 | 0.80 | PKM (0.49) | PKMMAPTALDH1A1POLBMEN1 | |
| SCHEMBL10731823 | 0.79 | MAPT (0.59) | PKMMAPTALDH1A1NPC1POLB | |
| SCHEMBL10730985 | 0.79 | MAPT (0.52) | PKMMAPTALDH1A1NPC1POLB | |
| SCHEMBL10729039 | 0.78 | PKM (0.56) | PKMMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |