Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716578 | 0.89 | PKM (0.49) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL10726196 | 0.82 | PKM (0.52) | PKMMAPTALDH1A1POLBCA1 | |
| SCHEMBL10726379 | 0.81 | PKM (0.47) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL10728346 | 0.81 | BAZ2B (0.48) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL10730568 | 0.81 | PKM (0.51) | PKMMAPTALDH1A1POLBCA1 | |
| SCHEMBL10727069 | 0.81 | ALDH1A1 (0.52) | PKMMAPTALDH1A1HCAR3P4HTM | |
| SCHEMBL10726719 | 0.79 | PKM (0.52) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL10717754 | 0.79 | ALDH1A1 (0.52) | PKMMAPTALDH1A1POLBCA1 | |
| SCHEMBL10731246 | 0.79 | PKM (0.45) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL10729011 | 0.78 | L3MBTL1 (0.50) | PKMMAPTHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |