Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10729011 | 0.85 | L3MBTL1 (0.50) | PKMMAPTHCAR3HDAC1HDAC3 | |
| SCHEMBL10728346 | 0.82 | BAZ2B (0.48) | PKMMAPTHCAR3HDAC1HDAC3 | |
| SCHEMBL10726379 | 0.82 | PKM (0.47) | PKMMAPTHDAC1HDAC3HDAC4 | |
| SCHEMBL10716578 | 0.82 | PKM (0.49) | PKMMAPTHCAR3HDAC1HDAC3 | |
| SCHEMBL10727069 | 0.79 | ALDH1A1 (0.52) | PKMMAPTHCAR3KDM4EALDH1A1 | |
| SCHEMBL10726333 | 0.79 | PKM (0.48) | PKMMAPTHCAR3HDAC1HDAC3 | |
| SCHEMBL10725561 | 0.77 | PKM (0.49) | PKMMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL10725612 | 0.76 | HCAR3 (0.46) | PKMMAPTHCAR3KDM4ELMNA | |
| SCHEMBL10726100 | 0.76 | GRM5 (0.60) | PKMMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL10726196 | 0.75 | PKM (0.52) | PKMMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |