Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10728346 | 0.85 | BAZ2B (0.48) | PKMMAPTKDM4EMAPK1L3MBTL1 | |
| SCHEMBL10716578 | 0.85 | PKM (0.49) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL10731246 | 0.82 | PKM (0.45) | PKMMAPTKDM4EMAPK1ALDH1A1 | |
| SCHEMBL10727069 | 0.82 | ALDH1A1 (0.52) | PKMMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL10726333 | 0.81 | PKM (0.48) | PKMMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL10729011 | 0.81 | L3MBTL1 (0.50) | PKMMAPTL3MBTL1ALDH1A1GAA | |
| SCHEMBL10725612 | 0.79 | HCAR3 (0.46) | PKMMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL10726100 | 0.78 | GRM5 (0.60) | PKMMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL13064470 | 0.78 | HDAC3 (0.62) | MAPTKDM4EMAPK1L3MBTL1KMT2A | |
| SCHEMBL10726196 | 0.78 | PKM (0.52) | PKMMAPTALDH1A1POLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |