Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147060 | 0.82 | ATAD2 (0.44) | ATAD2 | |
| SCHEMBL4273200 | 0.82 | ATAD2 (0.44) | ATAD2 | |
| SCHEMBL27589203 | 0.80 | GAA (0.39) | — | |
| SCHEMBL27663548 | 0.80 | LMNA (0.37) | KMT2ATDP1 | |
| SCHEMBL156784 | 0.80 | ATAD2 (0.48) | ATAD2 | |
| SCHEMBL4353311 | 0.79 | DPYD (0.50) | ATAD2 | |
| SCHEMBL161148 | 0.77 | ATAD2 (0.54) | ATAD2 | |
| SCHEMBL11149023 | 0.77 | ATAD2 (0.39) | ATAD2 | |
| SCHEMBL356483 | 0.77 | TYMP (0.49) | ATAD2 | |
| SCHEMBL17991873 | 0.76 | KMT2A (0.43) | POLBKMT2ATDP1ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125451-A1 | PIPERINDIN-ONES DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |
| US-4689321-A | CYTOLYSIS, ANTITUMOR, ANTICARCINOGENIC | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1987-08-25 | — | — | US | disclosed |