SCHEMBL11149023

SCHEMBL11149023

CS(=O)(=O)OCCc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ATAD2 Q6PL18 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27243730 0.91 KDM4E (0.41) ATAD2
SCHEMBL11147060 0.80 ATAD2 (0.44) ATAD2
SCHEMBL10726378 0.77 MEN1 (0.43) ATAD2
SCHEMBL4353311 0.76 DPYD (0.50) ATAD2
SCHEMBL27433771 0.73 DPYD (0.38) —
SCHEMBL29767278 0.73 HCAR2 (0.50) ATAD2
SCHEMBL156784 0.73 ATAD2 (0.48) ATAD2
SCHEMBL1546531 0.72 GAA (0.40) —
SCHEMBL27589203 0.71 GAA (0.39) —
SCHEMBL27663548 0.71 LMNA (0.37) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7777024-B2 Process for preparing a pentopyranosyl nucleic acid conjugate AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. (DE) 2010-08-17 — — US disclosed
US-20090221793-A1 PROCESS FOR PREPARING A PENTOPYRANOSYL NUCLEIC ACID CONJUGATE SANOFI-AVENTIS S.A. (FR) 2009-09-03 — — US disclosed
US-7501506-B2 Pentopyranosyl nucleic acid conjugates NANOGEN RECOGNOMICS GMBH (DE) 2009-03-10 — — US disclosed
US-4410530-A CARDIO-SELECTIVE B-RECEPTOR BLOCKING AGENTS AND STIMULANTS CIBA-GEIGY CORPORATION (US) 1983-10-18 — — US disclosed
US-4195090-A ADRENERGIC BLOCKING AGENTS CIBA-GEIGY CORPORATION (US) 1980-03-25 — — US disclosed
US-4115575-A CARDIOVASCULAR DISORDERS CIBA-GEIGY CORPORATION (US) 1978-09-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221793-A1 PROCESS FOR PREPARING A PENTOPYRANOSYL NUCLEIC ACID CONJUGATE RNGTT, NT5C3B, FUT6 ATAD2 4173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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