Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10731309 | 0.97 | KMT2A (0.46) | ALDH1A1KDM4EKMT2ATDP1ENPP3 | |
| SCHEMBL10717754 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KMT2ANPC1MAPTMAPK1 | |
| SCHEMBL10730985 | 0.79 | MAPT (0.52) | ALDH1A1KMT2ATDP1NPC1MAPT | |
| SCHEMBL10732444 | 0.79 | MAPT (0.49) | ALDH1A1KDM4EKMT2ANPC1MAPT | |
| SCHEMBL10726208 | 0.79 | PKM (0.52) | ALDH1A1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL10730945 | 0.77 | PKM (0.58) | ALDH1A1KDM4EKMT2ANPC1MAPT | |
| SCHEMBL10731823 | 0.77 | MAPT (0.59) | ALDH1A1KDM4EKMT2ANPC1MAPT | |
| SCHEMBL10726223 | 0.77 | NPC1 (0.49) | ALDH1A1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL10729295 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4EKMT2ANPC1MAPT | |
| SCHEMBL10727222 | 0.77 | MAPT (0.50) | ALDH1A1KDM4EKMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |