Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10731309 | 0.84 | KMT2A (0.46) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10730568 | 0.81 | PKM (0.51) | MAPTPOLBPKMGAAALDH1A1 | |
| SCHEMBL10728566 | 0.79 | ALDH1A1 (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10717754 | 0.79 | ALDH1A1 (0.52) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10726719 | 0.79 | PKM (0.52) | MAPTLMNAPOLBPKMNPC1 | |
| SCHEMBL10726196 | 0.79 | PKM (0.52) | MAPTLMNASMN1; SMN2POLBPKM | |
| SCHEMBL10731824 | 0.79 | PKM (0.49) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL10726331 | 0.77 | LMNA (0.59) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10729039 | 0.77 | PKM (0.56) | MAPTMEN1KMT2APKMCCR6 | |
| SCHEMBL10731727 | 0.76 | PKM (0.49) | MAPTLMNAPOLBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |