Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.40 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2888801 | 0.82 | ADCY8 (0.34) | GPBAR1ADCY8ADCY1ALKBH5DRD4 | |
| SCHEMBL2888804 | 0.82 | ADCY8 (0.34) | GPBAR1ADCY8ADCY1ALKBH5DRD4 | |
| SCHEMBL20919644 | 0.80 | HPGD (0.44) | — | |
| SCHEMBL27803229 | 0.78 | HTT (0.48) | GPBAR1ADCY8ADCY1ALKBH5LMNA | |
| SCHEMBL4683800 | 0.75 | ALDH1A1 (0.50) | LMNA | |
| SCHEMBL4686934 | 0.73 | POLB (0.45) | — | |
| SCHEMBL4686668 | 0.72 | KDM4E (0.48) | LMNA | |
| SCHEMBL1556921 | 0.72 | TAS1R3 (0.41) | — | |
| SCHEMBL15314434 | 0.72 | ADCY8 (0.43) | GPBAR1ADCY8ADCY1ALKBH5RARB | |
| SCHEMBL1070786 | 0.72 | SMN1; SMN2 (0.50) | ABCC9ABCC8KCNJ11KCNJ8NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271639-A2 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | Bayer CropScience AG (DE) | 2011-01-12 | — | — | EP | disclosed |
| US-20100286173-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-11 | — | — | US | disclosed |
| WO-2009090237-A2 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286173-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | HAAO, CYP51A1, HPD | GPBAR1 4680/4885ADCY8 4225/4885ADCY1 4419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.