Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 4/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732521 | 1.00 | HSD11B1 (0.46) | HSD11B1TAS2R14NFE2L2KEAP1PGR | |
| SCHEMBL10727300 | 0.88 | KMT2A (0.47) | HSD11B1KEAP1 | |
| SCHEMBL10727301 | 0.88 | KMT2A (0.47) | HSD11B1KEAP1 | |
| SCHEMBL10719220 | 0.86 | ALDH1A1 (0.45) | HSD11B1 | |
| SCHEMBL10731862 | 0.84 | MAPT (0.43) | KAT6A | |
| SCHEMBL10731857 | 0.84 | MAPT (0.43) | KAT6A | |
| SCHEMBL10731566 | 0.83 | PGR (0.41) | HSD11B1PGR | |
| SCHEMBL10731572 | 0.83 | PGR (0.41) | HSD11B1PGR | |
| SCHEMBL10731492 | 0.82 | PKM (0.47) | HSD11B1 | |
| SCHEMBL10731700 | 0.80 | CA1 (0.45) | PGRKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |