SCHEMBL1073369

SCHEMBL1073369

CC(C)(C)c1ccc(C(=O)O)cc1.CC(C)(C)c1ccc(C(=O)O)cc1.CCC(O)CCO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.56
RARB P10826 1/20 0.51
RARG P13631 1/20 0.51
NR1H4 Q96RI1 5/20 0.49
EPHX2 P34913 4/20 0.49
RXRA P19793 3/20 0.48
RXRB P28702 3/20 0.48
NR4A2 P43354 1/20 0.48
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
RXRG P48443 1/20 0.44
GAA P10253 2/20 0.44
ALPL P05186 1/20 0.44
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP1A2 P05177 1/20 0.43
MITF O75030 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17699395 0.86 SRD5A2 (0.61) SRD5A2RARBRARGNR1H4EPHX2
4-Methylbenzoic Acid SCHEMBL1786534 0.83 ALDH1A1 (0.57) SRD5A2RXRARXRBCA1CA2
Benzoic Acid SCHEMBL5081312 0.82 TSHR (0.50) SRD5A2GAAHTTMAPTSMN1; SMN2
Benzoic Acid SCHEMBL1073076 0.82 TSHR (0.50) SRD5A2GAAHTTMAPTSMN1; SMN2
SCHEMBL17699414 0.82 SRD5A2 (0.56) SRD5A2RARBRARGNR1H4EPHX2
Ethylene Glycol SCHEMBL21074269 0.82 SRD5A2 (0.74) SRD5A2RARBRARGNR1H4EPHX2
4-Chloro-Benzoic Acid SCHEMBL1081919 0.81 TSHR (0.55) SRD5A2EPHX2RXRARXRBNR4A2
SCHEMBL1070904 0.81 RXRA (0.43) RXRARXRBGAAHTTL3MBTL1
SCHEMBL5500996 0.81 SRD5A2 (0.62) SRD5A2RARBRARGNR1H4EPHX2
SCHEMBL17699388 0.81 SRD5A2 (0.62) SRD5A2RARBRARGNR1H4EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9068026-B2 Magnesium halide adducts, catalyst components and catalysts comprising the same, and preparation processes thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2015-06-30 US claimed
US-20120302708-A1 MAGNESIUM HALIDE ADDUCTS, CATALYST COMPONENTS AND CATALYSTS COMPRISING THE SAME, AND PREPARATION PROCESSES THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-11-29 US claimed
WO-2023072179-A1 OLEFIN POLYMERIZATION CATALYST COMPONENT, CATALYST SYSTEM, PREPOLYMERIZATION CATALYST COMPOSITION AND OLEFIN POLYMERIZATION METHOD 中国石油化工股份有限公司 2023-05-04 WO disclosed
EP-3486263-A2 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE W.R. Grace & CO. - CONN. (US) 2019-05-22 EP disclosed
US-10239969-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-03-26 US disclosed
EP-2185600-B1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE GRACE W R & CO (US) 2018-10-31 EP disclosed
EP-2225288-B1 SELF-LIMITING CATALYST COMPOSITION WITH BIDENTATE INTERNAL DONOR GRACE W R & CO (US) 2018-08-29 EP disclosed
US-9796796-B2 Self-limiting catalyst composition with No silane W. R. GRACE & CO.-CONN. (US) 2017-10-24 US disclosed
US-20170101486-A1 SPHERICAL MAGNESIUM HALIDE ADDUCT, A CATALYST COMPONENT AND A CATALYST FOR OLEFIN POLYMERIZATION PREPARED THEREFROM CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-04-13 US disclosed
US-9499569-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-11-22 US disclosed
EP-1666505-B1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2016-03-23 EP disclosed
US-20120302708-A1 MAGNESIUM HALIDE ADDUCTS, CATALYST COMPONENTS AND CATALYSTS COMPRISING THE SAME, AND PREPARATION PROCESSES THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-11-29 US disclosed
US-20120184694-A1 SPHERICAL MAGNESIUM HALIDE ADDUCT, A CATALYST COMPONENT AND A CATALYST FOR OLEFIN POLYMERIZATION PREPARED THEREFROM BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-07-19 US disclosed
EP-2454290-A1 SPHERICAL MAGNESIUM HALIDE ADDUCT, CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION PREPARED THEREFROM China Petroleum & Chemical Corporation (CN) 2012-05-23 EP disclosed
US-20110124491-A1 Self-Limiting Catalyst Composition with No Silane W. R. GRACE & CO.-CONN. 2011-05-26 US disclosed
WO-2011006278-A1 SPHERICAL MAGNESIUM HALIDE ADDUCT, CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION PREPARED THEREFROM CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2011-01-20 WO disclosed
US-20100273641-A1 Self-Limiting Catalyst Composition with Non-Phthalate Internal Donor W. R. GRACE & CO.-CONN. 2010-10-28 US disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10239969-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom MSMO1, SCO2, RTF1 SRD5A2 1065/4885RARB 3930/4885RARG 3903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.