Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732978 | 0.92 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL10742027 | 0.90 | PTGS2 (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL10733299 | 0.83 | KMT2A (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL10733297 | 0.74 | GPR84 (0.44) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3865315 | 0.72 | L3MBTL1 (0.71) | KMT2AMEN1ALDH1A1TDP1NPSR1 | |
| SCHEMBL5622616 | 0.72 | SMN1; SMN2 (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL6817343 | 0.70 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL5354612 | 0.70 | KMT2A (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7390217 | 0.70 | HDAC1 (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL28018754 | 0.70 | KMT2A (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4654360-A | 1,2,3-trisubstituted indoles for treatment of inflammation | SYNTEX (U.S.A.) INC. (US) | 1987-03-31 | — | — | US | disclosed |