Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 3/20 | 0.51 |
| ▸ | PTGIR | P43119 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291362 | 0.89 | PTGIR (0.60) | NPC1RAB9ASMN1; SMN2PTGIRHPGD | |
| SCHEMBL11079563 | 0.83 | RAB9A (0.71) | PTPN1PTPN11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6376610 | 0.81 | L3MBTL1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8238303 | 0.81 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL2092941 | 0.78 | SMN1; SMN2 (0.68) | PTPN1PTPN11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2056322 | 0.78 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4630959 | 0.77 | LMNA (0.56) | NPC1RAB9ASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL2054580 | 0.77 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2HTTNR1H4 | |
| SCHEMBL2092940 | 0.77 | PTPN1 (0.58) | PTPN1PTPN11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9128045 | 0.76 | ROCK2 (0.69) | NPC1RAB9ASMN1; SMN2ALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220848-A2 | 7-Oxabicycloheptane substituted amide-carbamate prostaglandin analogs | E.R. Squibb & Sons, Inc. (US) | 1987-05-06 | — | — | EP | disclosed |
| US-4652576-A | CARDIOVASCULAR DISORDERS, ANTICOAGULANTS | E. R. SQUIBB & SONS, INC. (US) | 1987-03-24 | — | — | US | disclosed |