Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10734313 | 0.85 | GLB1 (0.38) | — | |
| SCHEMBL10737685 | 0.76 | KIF11 (0.55) | KIF11 | |
| SCHEMBL2869646 | 0.73 | KIF11 (0.31) | KIF11 | |
| SCHEMBL2836589 | 0.70 | OPRK1 (0.35) | OPRK1 | |
| SCHEMBL14930410 | 0.69 | PNMT (0.41) | — | |
| SCHEMBL2835826 | 0.69 | RAD52 (0.32) | KIF11 | |
| SCHEMBL2835764 | 0.68 | GAA (0.40) | — | |
| SCHEMBL22905716 | 0.66 | PKM (0.44) | OPRK1 | |
| SCHEMBL4003083 | 0.66 | GRIN1 (0.51) | — | |
| SCHEMBL10738161 | 0.65 | KIF11 (0.44) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4636510-A | 4-phenyl-tetrahydro-furano-pyridines and anti-depressant pharmaceutical compositions containing same | BOEHRINGER INGELHEIM KG (DE) | 1987-01-13 | — | — | US | disclosed |
| EP-0123998-A2 | 4-Phenyl-tetrahydro-furano-pyridines, process for their preparation and pharmaceutical compositions | BOEHRINGER INGELHEIM KG (DE) | 1984-11-07 | — | — | EP | disclosed |