Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837226 | 0.78 | SLC6A2 (0.36) | — | |
| SCHEMBL2837064 | 0.74 | — | — | |
| SCHEMBL10740686 | 0.73 | OPRK1 (0.31) | KIF11 | |
| SCHEMBL2841889 | 0.71 | OPRM1 (0.35) | SIGMAR1 | |
| SCHEMBL4003083 | 0.70 | GRIN1 (0.51) | GRIN1GRIN2BSIGMAR1 | |
| SCHEMBL2841248 | 0.70 | KDM1A (0.35) | — | |
| SCHEMBL2835756 | 0.69 | PGR (0.38) | — | |
| SCHEMBL2837984 | 0.69 | OPRK1 (0.36) | GID4 | |
| SCHEMBL2838800 | 0.66 | NPC1 (0.42) | — | |
| SCHEMBL12344861 | 0.65 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141168-A1 | HETEROARYL DERIVATIVES | Nippon Shinyaku Co., Ltd. (JP) | 2010-01-06 | — | — | EP | disclosed |